mRNA level of ROCK1, RHOA, and LIMK2 as genes associated with apoptosis in evaluation of effectiveness of adalimumab treatment.
CONCLUSION: Adalimumab influences the expression of genes related to apoptosis and the values of dermatological indicators of patients. Changes in the expression level of genes associated with apoptosis suggest that ROCK1, RhoA, and LIMK2 may be genes that can potentially be indicators of treatment effectiveness and lack of response to biological treatment.
PMID: 32124389 [PubMed - as supplied by publisher]
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Krawczyk A, Strzałka-Mrozik B, Grabarek B, Wcisło-Dziadecka D, Kimsa-Dudek M, Kruszniewska-Rajs C, Gola J Tags: Pharmacol Rep Source Type: research
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