New benzimidazole-aldehyde hybrids as neuroprotectors with hypochlorite and superoxide radical-scavenging activity.
CONCLUSIONS: Our studies suggest that the benzimidazole-aldehyde hybrids act as direct ROS scavengers and membranes' stabilizers against free radicals. Thus, they play a role in the antioxidative defense system and have a promising potential as therapeutic neuroprotective agents for the treatment of neurodegenerative disorders.
PMID: 32125683 [PubMed - as supplied by publisher]
Source: Pharmacological Reports - Category: Drugs & Pharmacology Authors: Anastassova N, Yancheva D, Hristova-Avakumova N, Hadjimitova V, Traykov T, Aluani D, Tzankova V, Kondeva-Burdina M Tags: Pharmacol Rep Source Type: research
More News: Antidoxidants | Brain | Chemistry | Drugs & Pharmacology | Melatonin | Neurology | Pathology | Study | Toxicology