Gastric bypass improves weight loss, type 2 diabetes, study finds

People who are both severely obese and have type 2 diabetes may benefit from weight loss surgery, a new analysis suggests.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Authors: Zhang C, Cai W, Zhao H, Zhu M, Cui J, Sun Z Abstract To compare the clinical efficacy of gastric bypass in obese patients with T2DM with different BMI. Serum leptin, adiponectin, triglyceride (TG), cholesterol (CHOL) were measured as the indicators to show clinical efficacy after laparoscopic gastric bypass surgery (LRYGB). For patients with high BMI and patients with low BMI, the therapeutic effect of LRYGB surgical diabetes is more significant. The postoperative remission rate of diabetes in the high BMI group was not correlated with the preoperative lipid metabolism index but was positively correlated w...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
This randomized clinical trial compares the albuminuria-lowering effects of Roux-en-Y gastric bypass surgery vs best medical treatment in patients with early-stage chronic kidney disease, type 2 diabetes, and obesity.
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
The superiority of bariatric surgery over best medical therapy (BMT) in the treatment of type 2 diabetes has been well demonstrated in high-quality randomized clinical trials. Furthermore, there is sufficient clinical and mechanistic evidence to support consideration of metabolic surgery for the patients with class 1 obesity (body mass index [BMI], 30.0-34.9; calculated as weight in kilograms divided by height in meters squared), type 2 diabetes, and inadequately controlled hyperglycemia. At 5-year follow-up, compared with BMT, the Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (ST...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a ...
Source: Diabetes Core Update - Category: Endocrinology Authors: Source Type: podcasts
Obesity is a world-wide epidemic and it is a risk factor for type 2 diabetes (T2D). Few randomized controlled studies have compared the 2 most common surgical procedures, Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in the treatment of obese patients with T2D.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original article Source Type: research
Obesity is a world-wide epidemic and it is a risk factor for type 2 diabetes mellitus (T2D). Few randomized controlled studies have compared the two most common surgical procedures, Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in the treatment of obese subjects with T2D.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
CONCLUSION: Bariatric surgery might cause reduction of thyroid replacement dosage in hypothyroid, morbidly obese patients. PMID: 32409116 [PubMed - as supplied by publisher]
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Tags: Surg Obes Relat Dis Source Type: research
Background: N-acetylaspartate (NAA) is synthesized only by neurons and is involved in neuronal metabolism and axonal myelination. NAA is the strongest signal on brain magnetic resonance spectroscopy, and its concentration have been associated with cognitive dysfunction in neurodegenerative diseases, obesity, and type 2 diabetes (T2D).Materials and Methods: We explored the impact of obesity and T2D on circulating NAA as well as the impact of bariatric surgery and antidiabetic treatments. We developed an LC-MS method for the accurate measurements of fasting plasma NAA levels in 505 subjects (156 subjects with normal glucose ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Obesity is a serious, chronic, treatable, and global disease epidemic. Over 98 million people currently have the disease of obesity, and in a recent New England Journal of Medicine article, Harvard researchers predicted that by 2030, 50% of the population in the United States will have the disease of obesity. Type 2 diabetes (T2D) is significantly associated with obesity. While many people with obesity do not have diabetes, most people with T2D have the disease of obesity. Excess adiposity (body fat storage), which is present in obesity, contributes to many chronic diseases beyond T2D. These include high blood pressure, he...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Diabetes Diet and Weight Loss Health Heart Health Surgery Source Type: blogs
CONCLUSION: Roux-en-Y gastric bypass successfully reduced weight, BMI, and comorbidities and medication use and cost at 24 months in Brazilian patients treated in the public Unified Health System.
Source: Clinics - Category: General Medicine Source Type: research
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