Impact of anti-epileptic drug choice on discharge in acute traumatic brain injury patients

ConclusionIn this cohort, using Phenytoin for acute TBI, seizure prophylaxis was associated with longer length of stay and more dizziness compared to Levetiracetam. Given their equivalent AED efficacy in acute TBI seizure prophylaxis, our data suggest that Levetiracetam is preferable to Phenytoin for early seizure prophylaxis in TBI. This requires evaluation in larger, prospective studies.

http://link.springer.com/10.1007/s00415-020-09769-5

Source: Journal of Neurology - March 3, 2020 Category: Neurology Source Type: research