Overexpression of Adiponectin Improves Neurobehavioral Outcomes After Focal Cerebral Ischemia in Aged Mice.

CONCLUSIONS: Our results demonstrate that APN overexpression reduces ischemic brain injury and improves neurobehavioral function recovery in aged mice than in young mice, suggesting APN is more beneficial in aged animals after ischemic stroke.
PMID: 24164711 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - October 25, 2013 Category: Neuroscience Authors: Miao J, Shen LH, Tang YH, Wang YT, Tao MX, Jin KL, Zhao YJ, Yang GY Tags: CNS Neurosci Ther Source Type: research