Association between CYP2B6 polymorphism and acute leukemia in a Han population of Northwest China

ConclusionOur findings show a strong correlation of theCYP2B6 c.516G>T polymorphism in the Han population of Northwest China with AL, especially fusion gene ‐positive AL, and indicate a poor prognosis after the first course of chemotherapy. Our findings also implicate the T allele in AL susceptibility and indicate the existence of racial and geographical differences in allele frequencies ofCYP2B6 c.516G>T polymorphism.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research