Acquired pure red cell aplasia following recombinant erythropoietin (darbepoetin-alfa) therapy

Somanath Padhi, Gayatri Behera, Sandeep Abhijit Pattnaik, Prabodh Kumar Das, Amit Kumar Adhya, Susama PatraIndian Journal of Nephrology 2020 30(2):113-116 Acquired pure red cell aplasia (PRCA) following use of recombinant erythropoietin (rEPO) is distinctly rare and sporadically reported in the literature. We discuss a case of PRCA following the usage of rEPO (darbepoetin-α) during the management of anemia of chronic kidney disease in an elderly male subject with review of literature and a brief insight into proposed pathophysiologic mechanism, diagnosis, and management.
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research