Evaluation of Mutations in 23S rRNA , rdxA and frxA Genes of Helicobacter pylori in Paraffin-Embedded Gastric Biopsy Specimens from Iranian Gastric Cancer and Gastritis Patients

ConclusionA2143G mutation is the most frequent mutation among clarithromycin resistant genes in Iran. Also, missense and frameshift mutations are frequent inrdxA andfrxA genes. Screening for these mutations could help researchers to investigate the most effective anti-H. pylori antibiotics and to prevent antibiotic resistance.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research