The First Case Report of Septic Arthritis and Osteomyelitis of the Knee Caused by Candida viswanathii

An elderly lady was diagnosed in 2015 with septic arthritis and osteomyelitis of the knee caused by Candida viswanathii. This is the first report of a nonmeningitic, noncandidemic osteoarticular infection due to this rare Candida since the first 2 isolations in cerebrospinal fluid in 1959 and 1976, respectively. She was successfully treated with 2 repeat arthroscopic washouts and 16 months of susceptible antifungal therapy with full recovery. The contributing factors of this successful treatment include prompt molecular identification of this rare Candida species, adequate source control with arthrotomies, susceptibility directed antifungal therapy, therapeutic drug monitoring of voriconazole, and close follow-up of our patient. To our understanding, this is also the first reported case of invasive C. viswanathii infection with detailed clinical presentation, treatment method, and treatment response described.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research