The implications of late-life cannabis use on brain health: A mapping review and implications for future research.
The implications of late-life cannabis use on brain health: A mapping review and implications for future research. Ageing Res Rev. 2020 Feb 25;:101041 Authors: Weinstein G, Sznitman SR Abstract While medical and recreational cannabis use is becoming more frequent among older adults, the neurocognitive consequences of cannabis use in this age group are unclear. The aim of this literature review was to synthesize and evaluate the current knowledge on the association of cannabis use during older-adulthood with cognitive function and brain aging. We reviewed the literature from old animal models and human studies while focusing on the link of middle- and old-age use of cannabis with cognition. The report highlights the gap in knowledge on cannabis use in late-life and cognitive health, and discusses the limited findings in the context of substantial changes in attitudes and policies. Furthermore, we outline possible theoretical mechanisms and propose recommendations for future research. The limited evidence on this important topic suggests that use in older ages may not be linked with poorer cognitive performance, thus detrimental effects of early-life cannabis use may not translate to use in older ages. Rather, use in old ages may be associated with improved brain health, in accordance with the known neuroprotective properties of several cannabinoids. Yet, firm conclusions cannot be drawn from the current evidence-base due to lack of research with strong me...
Authors: Messaadi N, Bayen S, Beghin L, Lefebvre JM, Colleau S, Deken V, Cottencin O, Quersin F, Descamps A, Vanhelst J Abstract BACKGROUND: Screen media usage has become increasingly commonplace in daily life with children initiating themselves to screen media at an early age. Given the high prevalence of screen viewing among children worldwide, its impact on children's health has become a cause for concern. Unfortunately, little information on the independent association between sleep habits and screen time in French children is currently available. The main aim of this study was to assess possible...
Publication date: Available online 28 May 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Aline Bayerle, Christian Marsching, Mariona Rabionet, Shaalee Dworski, Mustafa A. Kamani, Chandramohan Chitraju, Nina L. Gluchowski, Katlyn R. Gabriel, Silke Herzer, Richard Jennemann, Thierry Levade, Jeffrey A. Medin, Roger Sandhoff
PMID: 32464083 [PubMed - as supplied by publisher]
Conclusions: EVs from buffaloes infected with Theileria spp. were successfully isolated and characterized. This is an advance in the knowledge of host-parasite relationship that contributes to the understanding of host immune response and theileriosis evasion mechanisms. These findings may pave the way for searching new EVs candidate-markers for a better production of safe biological products derived from buffaloes.
Conclusions: JZTX-X selectively suppresses Kv4.2 and Kv4.3 potassium channe l activity in a concentration- and voltage-dependent manner and causes long-lasting mechanical hyperalgesia.
Conclusion: Our results suggest a different biochemical composition of S. polymorpha venom, based on the different effects of four venom fractions on the cells tested, according to statistical evidence. Fractions F6 and F7 caused the most important alterations.
Publication date: Available online 29 May 2020Source: The Annals of Thoracic SurgeryAuthor(s): Irsa S. Hasan, Hartzell V. Schaff, Richard C. Daly, Katherine S. King, John M. Stulak, Kevin L. Greason, Joseph A. Dearani
Publication date: Available online 29 May 2020Source: The Annals of Thoracic SurgeryAuthor(s): Takafumi Ouchi, Noriyuki Kato, Hiroaki Kato, Takatoshi Higashigawa, Hisato Ito, Ken Nakajima, Shuji Chino, Toshiya Tokui, Toru Mizumoto, Hajime Sakuma
Publication date: September 2020Source: Interdisciplinary Neurosurgery, Volume 21Author(s): Nobuya Murakami, Takato Morioka, Satoshi O. Suzuki, Nobutaka Mukae, Takafumi Shimogawa, Yoshihiro Matsuo, Takakazu Sasaguri, Masahiro Mizoguchi
Publication date: September 2020Source: Interdisciplinary Neurosurgery, Volume 21Author(s): Zachary K. Christian, Kimmo J. Hatanpaa, Richard J. Auchus, Stephen R. Hammes, Ankur R. Patel, Bruce E. Mickey