Main Quest, Subquest, Side Quest, or Minigame

This was an idea that came up in a discussion thread in Conscious Growth Club this week, and I thought it might make an interesting article. You may like this way of thinking if you’re into video games, especially games that involve different types of quests. Main Quest Your main quest is whatever you consider most important in life right now. This could be your life purpose or mission. It could be your alignment with certain values that you consider sacred. It could be a major transition that you’re considering or facing. In a game you main quest is whatever goal you must eventually accomplish in order to complete the game and activate the victory sequence. That could be defeating a major opponent, saving the world, solving a mystery, etc. Your purpose for playing games is probably to have fun. Making progress towards your main quest is part of what makes the game fun and interesting. It’s also rewarding to finish games that have an ending, so keeping the main quest in mind is wise if you eventually want to finish. However, the main quest in a big game can often feel pretty distant, especially early in the game. So most of the time, you’re probably not focusing on the main quest directly, even when other characters remind you of it repeatedly. You may not even be capable of directly working on the main quest, such as if you cannot find or access the main opponent that you’re supposed to defeat. Subquest A subquest is a small...
Source: Steve Pavlina's Personal Development Blog - Category: Psychiatry & Psychology Authors: Tags: Lifestyle Productivity Source Type: blogs

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Psychologists say anxiety and uncertainty prompt irrational decisions — like turning down a transplant when an organ becomes available.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Transplants Emergency Medical Treatment Coronavirus (2019-nCoV) Liver Fear (Emotion) Anxiety and Stress Cancer Heart your-feed-science your-feed-healthcare Source Type: news
AbstractAdvances in surgery and pediatric care over the past decades have achieved improved survival for children born with congenital heart disease (CHD) and have produced a large, growing population of patients with adult congenital heart disease (ACHD). Heart failure has emerged as the leading cause of death and a major cause of morbidity among the ACHD population, while as little evidence supports the efficacy of guideline-directed medical therapies in this population. It is increasingly important that clinicians caring for these patients understand how to utilize mechanical circulatory support (MCS) in ACHD. In this r...
Source: Heart Failure Reviews - Category: Cardiology Source Type: research
We report a case of 2019-nCoV pneumonia with associated acute myocardial injury2 confirmed by biomarkers as well as cardiac Magnetic Resonance Imaging (MRI).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research
Publication date: Available online 27 May 2020Source: Respiratory Medicine Case ReportsAuthor(s): Lea Deterding, Tina Körner, Gudrun Borte, Hubert Wirtz, Hans-Jürgen Seyfarth
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
The program has been dormant for more than eight years.
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
The absence of alloantibodies is a feature of transplantation tolerance. Although the lack of T cell help has been evoked to explain this absence, herein we provide evidence for B cell–intrinsic tolerance mechanisms. Using a murine model of heart tolerance, we showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies. We inferred that tolerant alloreactive B cells retained their ability to sense alloantigen because they continued to drive T cell maturation into CXCR5+PD-1+ T follicular helper cells. Unexpectedly...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
The original article omits an affiliation for authors, He Zhang and Dongjin Wang. The omitted affiliation can be viewed in this Correction article.
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Correction Source Type: research
Of the four major solid organ transplants, median survival following lung transplantation (LTx) remains the shortest (5.7-5.8 years) with negligible improvements reported over the last decade due to high rates of chronic lung allograft dysfunction (CLAD), a progressive and ultimately fatal complication limiting long-term survival in transplantees.1 Bronchiolitis obliterans syndrome (BOS), often dubbed the “Achilles Heel” of lung transplantation, is the most common manifestation of CLAD and is resistant to most current treatment modalities, leaving repeat lung transplantation (re-LTx) the only treatment option.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Research Correspondence Source Type: research
Abstract Rescuing patients with the development of acute respiratory distress syndrome and right heart failure after left ventricular assist device placement remains a challenge in patients with congenital heart disease. TandemLife Protek Duo (TandemLife, Pittsburg, PA) is a double-lumen cannula introduced via the internal jugular vein that can provide veno-venous extra-corporeal membrane oxygenation and right heart support. To our knowledge, we report the first case of successfully using the TandemLife Protek Duo cannula to provide veno-venous extra-corporeal membrane oxygenation and right ventricle support in an...
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Authors: den Exter PL, Beeres SLMA, Eikenboom J, Klok FA, Huisman MV Abstract INTRODUCTION: The treatment options for advanced heart failure patients drastically changed with the introduction of left ventricular assist devices (LVADs), either as bridge to transplant or as destination therapy for patients ineligible for transplant. Despite major benefits in terms of survival, functional status and quality of life, managing patients with LVADs comes with several challenges. The most significant challenge is balancing between the risks of thrombotic and bleeding complications. AREAS COVERED: The present review des...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
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