Serum and synovial fluid interleukin-17 concentrations in rheumatoid arthritis patients: Relation to disease activity, radiographic severity and power Doppler ultrasound

Publication date: Available online 28 February 2020Source: The Egyptian RheumatologistAuthor(s): Medhat A. Farag, Fouad E. El Debaky, Shaymaa M. Abd El-Rahman, Samah M. Abd el-khalek, Rasha M. Fawzy
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research

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Purpose of review Musculoskeletal ultrasonography (MSUS) and magnetic resonance imaging (MRI) play important roles in diagnosis, monitoring, and prognostication of rheumatoid arthritis. This review highlights recent literature in this field and aims to provide insight into the future use in clinical practice. Recent findings Recent studies concerning the use of MSUS and MRI in clinical practice show how MSUS and MRI can improve diagnosis and monitoring of rheumatoid arthritis and how they can predict both radiographic progression and clinical outcome (e.g., successful tapering of medical treatment). Moreover, novel te...
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: RHEUMATOID ARTHRITIS: Edited by Joshua F. Baker Source Type: research
CONCLUSION: Ultrasound could be as sensitive and specific as contrast-enhanced MRI for the diagnosis of subclinical synovitis and tenosynovitis.
Source: Clinics - Category: General Medicine Source Type: research
ConclusionThis review of relevant studies indicates that US should become accepted as the investigation with the most favourable balance of benefits to risks in the early diagnosis of RA. Given the continuing controversy surrounding studies of different imaging techniques in RA, further research into the diagnostic role of US in RA is indicated.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
Conclusions: PET/CT images provide unique quantitative information that cannot be obtained from any other imaging modalities.
Source: Quintessence International - Category: Dentistry Source Type: research
CONCLUSION: The RA-BIODAM prospective study succeeded in generating an extensive list of clinical, imaging (2343 radiographs), and biosample (4638 sera) resources that will be made available to expedite the identification and validation of biomarkers for radiographic damage endpoints. PMID: 31474600 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
Conclusions The US demonstrated to be useful to help accurately classify as RA patients previously diagnosed with UA.
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research
AbstractThe management of patients with rheumatoid arthritis (RA) has rapidly evolved with the development of newer disease-modifying drugs and the recognition that long-term damage can be mitigated by an earlier and more-informed use of these medications. Historically, radiographs were the mainstay of imaging in RA patients, but radiographic joint narrowing and erosions are late and insensitive findings in the disease. MRI (with intravenous contrast agent) and ultrasound (with power Doppler interrogation) of the hands and wrists are able to demonstrate erosions earlier and with greater sensitivity than radiographs. More i...
Source: Skeletal Radiology - Category: Radiology Source Type: research
AbstractOver the last decades, ultrasound (US) has undergone a dramatic evolution in the field of inflammatory joint diseases. Rheumatoid arthritis (RA) is probably the pathology that has most benefited from this development, both in terms of early diagnosis and monitoring of disease activity. The RA-induced morpho-structural changes can be effectively detected and measured by US, and US findings represent an additional advantage over clinical and laboratory evaluation, showing the face of the disease (i.e., proliferative synovitis) and revealing its aggressive behavior (i.e., presence of bone erosions not detectable by co...
Source: La Radiologia Medica - Category: Radiology Source Type: research
Publication date: Available online 31 January 2019Source: Joint Bone SpineAuthor(s): Camille Roux, Frédérique Gandjbakhch, Audrey Pierreisnard, Marion Couderc, Cédric Lukas, Racha Masri, Jean-Philippe Sommier, Isabelle Clerc-Urmes, Cédric Baumann, Isabelle Chary-Valckenaere, Damien LoeuilleAbstractObjectives: The aims of this study were to compare characteristics of radiography (RX) and ultrasound (US) erosive lesions in rheumatoid arthritis (RA) and osteoarthritis (OA) patients (prevalence, topography and severity), to determine thresholds for the diagnosis of erosive RA based on US and to eval...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: March 2018Source: The Egyptian Heart Journal, Volume 70, Issue 1Author(s): Ghada Youssef, Nashwa Taher Allam, Wafaa Gaber, Angie Afifi, Dina HeshamAbstractBackgroundRheumatoid arthritis (RA) is associated with elevated plasma level of inflammatory markers. Chronic inflammation is known to predispose to endothelial dysfunction and increased arterial stiffness, which is an important marker of subclinical atherosclerosis and increased cardiovascular risk.ObjectiveThe aim is to test for the relationship between disease activity and arterial stiffness in RA patients.MethodsThe study included 90 RA patients, at...
Source: The Egyptian Heart Journal - Category: Cardiology Source Type: research
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