Current Insights of Inhibitors of p38 Mitogen-Activated Protein Kinase in Inflammation.

CONCLUSION: Development of successful selective p38MAPK inhibitors in inflammatory diseases are in progress despite of all challenges. It was speculated that p38MAPK also plays an important role in treating diseases such as neuroinflammation, arterial inflammation, vascular inflammation, cancer and so on which are posing the world with treatment challenges. In this review, clinical trials of drugs are discussed related to inflammatory and its related diseases. Research is in progress to design and develop novel p38MAPK inhibitors with minimal side effects. PMID: 32106802 [PubMed - as supplied by publisher]
Source: Medicinal Chemistry - Category: Chemistry Authors: Tags: Med Chem Source Type: research