RSV Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells.

CONCLUSIONS: Pneumovirus infection induces AEC necroptosis. Inhibition of necroptosis may be a viable strategy to limit the severity of viral bronchiolitis and break its nexus with asthma.
PMID: 32105156 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory and Critical Care Medicine - February 26, 2020 Category: Respiratory Medicine Authors: Simpson J, Loh Z, Ullah MA, Lynch JP, Werder RB, Collinson N, Zhang V, Dondelinger Y, Bertrand MJM, Everard ML, Blyth CC, Hartel G, Van Oosterhout AJ, Gough PJ, Bertin J, Upham JW, Spann KM, Phipps S Tags: Am J Respir Crit Care Med Source Type: research