Inhibition of microRNA-15 protects H9c2 cells against CVB3-induced myocardial injury by targeting NLRX1 to regulate the NLRP3 inflammasome.

Conclusion: Our results indicate that miR-15 inhibition alleviates CVB3-induced myocardial inflammation and cell injury. This may be partially due to NLRX1-mediated NLRP3 inflammasome inactivation. PMID: 32099552 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32099552?dopt=Abstract

Source: Cellular and Molecular Biology Letters - February 28, 2020 Category: Biochemistry Authors: Tong R, Jia T, Shi R, Yan F Tags: Cell Mol Biol Lett Source Type: research