Histopathologic and physiologic effect of bifurcation stenting: current status and future prospects.

Histopathologic and physiologic effect of bifurcation stenting: current status and future prospects. Expert Rev Med Devices. 2020 Feb 26;:1-12 Authors: Cornelissen A, Guo L, Sakamoto A, Jinnouchi H, Sato Y, Kuntz S, Kawakami R, Mori M, Fernandez R, Fuller D, Gadhoke N, Kolodgie FD, Surve D, Romero ME, Virmani R, Finn AV Abstract Introduction: Coronary bifurcation lesions are involved in up to 20% of all percutaneous coronary interventions (PCI). However, bifurcation lesion intervention is associated with a high complication rate, and optimal treatment of coronary bifurcation is an ongoing debate.Areas covered: Both different stenting techniques and a variety of devices have been suggested for bifurcation treatment, including the use of conventional coronary stents, bioresorbable vascular scaffolds (BVS), drug-eluting balloons (DEB), and stents dedicated to bifurcations. This review will summarize different therapeutic approaches with their advantages and shortcomings, with special emphasis on histopathologic and physiologic effects of each treatment strategy.Expert opinion: Histopathology and clinical data have shown that a more simple treatment strategy is beneficial in bifurcation lesions, achieving superior results. Bifurcation interventions through balloon angioplasty or placement of stents can importantly alter the bifurcation's geometry and accordingly modify local flow conditions. Computational fluid dynamics (CFD) studies have shown that the outco...
Source: Expert Review of Medical Devices - Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

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One of the main causes of chest pain is a blockage of blood flow down the coronary arteries, the blood vessels that deliver oxygenated blood to our heart muscle to allow it to beat. Depending on how fast the blockage forms, it is labeled as either a stable or unstable blockage. Unstable blockages occur quickly when an atherosclerotic plaque ruptures within the coronary artery and a clot forms on top of it. The clot, along with the plaque, can obstruct blood flow, deprive heart muscle of oxygen, and lead to a heart attack. This is called an acute coronary syndrome, and it frequently requires a minimally invasive procedure c...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Heart Health Tests and procedures Source Type: blogs
Condition:   Peripheral Artery Disease Intervention:   Device: AcoArt Orchid (0.035 " ), AcoArt Tulip (0.018 " ) and AcoArt Litos (0.014 " ) percutaneous transluminal angioplasty (PTA) paclitaxel drug coated balloon catheter manufactured by Acotec Scientific Co., Ltd. Sponsor:   Acotec Scientific Co., Ltd Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: British Journal of Neurosurgery - Category: Neurosurgery Authors: Source Type: research
Endovascular interventions are commonly utilized for treatment of femoropopliteal peripheral artery disease. The relative efficacy of these interventions remains unclear. A Bayesian network meta-analysis was performed comparing 5 endovascular treatment modalities: balloon angioplasty (BA), bare metal stent (BMS), covered stent (CS), drug coated balloon (DCB), drug eluting stent (DES) for femoropopliteal peripheral artery disease. The primary efficacy endpoints were freedom from target lesion revascularization (TLR) and primary patency at 12 months.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Kajari Bhattacharya, Biswajit Paul, Sukalyan PurkayasthaNeurology India 2020 68(2):504-506
Source: Neurology India - Category: Neurology Authors: Source Type: research
CONCLUSIONS: This study is the first to analyze safety and feasibility of a high-pressure, noncompliant balloon for long, calcified infrapopliteal and inframalleolar lesions. PMID: 32401473 [PubMed - as supplied by publisher]
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
Semin intervent Radiol 2020; 37: 207-213 DOI: 10.1055/s-0040-1709207There is no consensus for the treatment of a tandem occlusion (TO) in a patient presenting with an acute ischemic stroke. In this review article, we will focus on the controversial treatment strategies for TOs. First, we will discuss treatment options including retrograde, antegrade, and delayed approaches. Second, the role of carotid stent placement versus balloon angioplasty for the extracranial occlusion will be presented. Third, anticoagulation and antiplatelet regimens for the treatment TOs published in the literature will be reviewed. Finally, we wil...
Source: Seminars in Interventional Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
AbstractPaclitaxel has a potentially beneficial effect on atherosclerotic plaque volume reduction; however, data about plaque volume reduction in real-world practice are scarce. We herein report a case whose plaque volume of superficial femoral artery was analyzed using high-definition intravascular ultrasound just after endovascular treatment using drug-coated balloon and at 6  months after the procedure. From analysis using a quantitative intravascular ultrasound analysis system, the lumen volume was enlarged (from 2909.2 to 4944.1 mm3) as a result of not only vessel volume enlargement (from 7242.0 to 8296.3 &n...
Source: Cardiovascular Intervention and Therapeutics - Category: Cardiology Source Type: research
This study investigated the safety and effectiveness of the Tack Endovascular System in patients with dissections after drug-coated balloon (DCB) angioplasty.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Authors: Tzanis G, Kolyviras A, Giannini F, Colombo A, Tzifos V Abstract The rePOT technique is a novel and easy applicable approach for coronary bifurcations. Drug coated balloon (DCB) angioplasty is a technology increasingly being utilized in the management of small vessels and coronary bifurcation lesions. Herewith we propose a new approach for coronary bifurcation lesions with the application of DCB to treat the side-branch in addition to the rePOT technique, the POT-sideDCB-POT technique. PMID: 32387590 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - Category: Cardiology Tags: Hellenic J Cardiol Source Type: research
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