Alternative therapies for sinusitis and rhinitis: a systematic review utilizing a modified Delphi method

ConclusionSome alternative therapies show promise as potential treatments for sinusitis and rhinitis, mostly compared to placebo. Comparisons to traditional therapies are lacking. For other alternative therapies, many websites included unsubstantiated claims of benefit and ignored potential side effects for which patients should be warned appropriately.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Conclusions: Component resolved diagnostic testing toward the major allergen Asp f 1 was less sensitive than skin prick test and serology toAspergillus fumigatus protein extract. However, sensitivity of component resolved diagnostics might be underestimated. Diagnostics of the species-specific allergens Asp f 1, 2, and 4 might allow to differentiate between genuine and cross-reactive sensitization. In the clinical routine, skin prick test and serology to crude extract remain the methods of choice.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Authors: Won JY, Kwon JW, Hong SN, Lee WH Abstract Background: The association between pet sensitization and pet ownership remains unclear. We elucidated the association between pet sensitization and pet ownership by age. Methods: We retrospectively reviewed 2883 patients who visited our allergy clinic for nasal symptoms from January 2003 to December 2014; 1957 patients with data on skin-prick tests and questionnaire responses were included, and divided into adult (age>19) and children (≤19) groups; the association between pet sensitization and pet ownership was evaluated in both groups. Results: Amon...
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
CONCLUSIONS: AD incidence in our cohort was high and several risks factors were related to AD. PMID: 32402624 [PubMed - as supplied by publisher]
Source: Allergologia et Immunopathologia - Category: Allergy & Immunology Authors: Tags: Allergol Immunopathol (Madr) Source Type: research
Chronic rhinosinusitis (CRS) is a common medical problem, frequently seen by those in primary care, allergy, and otolaryngology. Our understanding of chronic sinusitis is continuously evolving, with some recent substantial advancements in the knowledge of the pathophysiology of CRS and new treatment options. For example, there is a greater understanding of how the environment, through allergic rhinitis, air pollution, and the patient ’s own microbiome, may play a role in the development of CRS. The recognition of CRS as an inflammatory disease state has been further refined, but trying to define the disease in terms ...
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Tags: Preface Source Type: research
We examined the impact of mepolizumab on clinically significant exacerbations and health-related quality of life (HRQoL) in patients with severe eosinophilic asthma and upper respiratory comorbidities.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
We present here the studies on the nasal microbiota in healthy infants, allergic rhinitis, and CRS. The results demonstrate that there are stable and unstable profiles of microbiota during infancy. Decreased diversity or an imbalance of the microbial composition could be an important factor in the development of both allergic rhinitis and CRS. We also discuss here several recent animal and human studies that demonstrate the effect of probiotics in allergic rhinitis and chronic rhinosinusitis. Results from human studies (clinical trials) have demonstrated that probiotics may be effective for allergic rhinitis, but there are...
Source: Current Opinion in Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: RHINITIS, SINUSITIS AND UPPER AIRWAY DISEASE: Edited by Ruby Pawankar and David P. Skoner Source Type: research
AbstractPurpose of ReviewOccupational rhinitis (OR), an inflammatory disease of the nose, refers to any nasal symptoms reported to be work-related. The purpose of this review is to provide a current overview of the classification, diagnosis, and treatment of OR.Recent FindingsOccupational rhinitis (OR) can further be  classified into allergic or non-allergic depending on the causative agent(s) and pathogenesis. Presenting symptoms are similar to non-OR including nasal congestion, anterior and posterior rhinorrhea, sneezing, and nasal itching. Despite its high prevalence in a spectrum of workplaces, OR is under reporte...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Conclusions: Allergic rhinitis is common comorbidity of asthma that interrelated to asthma control. Identifiable allergens could be detected AR in asthma by SPT. Therefore, reduction of allergens exposure could become preventive approach for asthma patients with AR.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Allergy and immunology Source Type: research
Patients with asthma often experience nasal symptoms, from comorbid allergic rhinitis and sinusitis to nasal polyposis. We evaluated reductions in nasal symptoms as a function of baseline blood eosinophil counts (BEC) for patients in a Phase IIb study of benralizumab.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Source Type: research
ConclusionsSM are a  common sensitization in the study population and should be included in standard skin prick test arrays. Cross sensitization to house dust mites is limited and nasal symptoms are most frequent. Nasal provocation testing is necessary to secure clinical diagnosis of allergy and further research is ne eded to evaluate the clinical relevance of the high sensitization rates found for intradermal testing.
Source: Allergo Journal International - Category: Allergy & Immunology Source Type: research
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