Commentary: Prevention of Systolic Anterior Motion after Mitral Repair in Hypertrophic Obstructive Cardiomyopathy: One Simple Stitch Fits All?

Left ventricular outflow tract (LVOT) obstruction due to systolic anterior motion (SAM) of the mitral valve (MV) is a frequent cause of disabling symptoms hypertrophic obstructive cardiomyopathy (HOCM).1 This phenomenon has a wide clinical spectrum with varying severity and can be associated, in severe cases, with hemodynamic instability due to LVOT obstruction and/or mitral regurgitation (MR).2 The following 3 main pathophysiological risk factors, or a combination thereof, can lead to SAM in patients with HOCM: (1) reduced coaptation-septum distance; (2) elongated anterior mitral leaflet (AML) and/or posterior mitral leaflet (PML); and (3) increased flow velocity into the LVOT (Venturi effect).
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ADULT – Commentary Source Type: research