18q12.3 ‐q21.1 microdeletion detected in the prenatally alcohol‐exposed dizygotic twin with discordant fetal alcohol syndrome phenotype

ConclusionsThe microdeletion emphasizes the importance of adequate chromosomal testing in examining the etiology of complex alcohol ‐induced developmental disorders. Furthermore, the genotype‐specific decreased DNA methylation at theIGF2/H19 locus cannot be considered as a biological mark for PAE in adult WBCs.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research