Study: Metformin for breast cancer less effective at higher glucose concentrations

(University of Colorado Denver) A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome. The study also showed that patients with high glucose may require higher doses of the drug metformin to achieve the same anti-cancer activity as patients with normal glucose levels.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news