Cardiac biomarkers for the detection of cardiotoxicity in childhood cancer —a meta‐analysis

ConclusionsBNP/NT ‐proBNP is associated with cardiotoxicity in paediatric cancer patients receiving anthracycline therapy, but owing to low sensitivity, BNP/NT‐proBNP has to be evaluated in the context of further parameters including clinical assessment and echocardiography. Future studies are needed to determine whether troponin serves as a marker for cardiotoxicity in children. Standardized recommendations for the application of cardiac biomarkers in children undergoing cardiotoxic cancer therapy may benefit management and clinical outcome.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research