Cardiac biomarkers for the detection of cardiotoxicity in childhood cancer —a meta‐analysis
ConclusionsBNP/NT ‐proBNP is associated with cardiotoxicity in paediatric cancer patients receiving anthracycline therapy, but owing to low sensitivity, BNP/NT‐proBNP has to be evaluated in the context of further parameters including clinical assessment and echocardiography. Future studies are needed to determine whether troponin serves as a marker for cardiotoxicity in children. Standardized recommendations for the application of cardiac biomarkers in children undergoing cardiotoxic cancer therapy may benefit management and clinical outcome.
Source: ESC Heart Failure - Category: Cardiology Authors: Lars Michel,
Raluca I. Mincu,
Simone M. Mrotzek,
Sebastian Korste,
Ulrich Neudorf,
Tienush Rassaf,
Matthias Totzeck Tags: Original Research Article Source Type: research
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