IL-8 as a potential biomarker in Guillain-Barre Syndrome.

IL-8 as a potential biomarker in Guillain-Barre Syndrome. Eur Cytokine Netw. 2019 Dec 01;30(4):130-134 Authors: Breville G, Lascano AM, Roux-Lombard P, Lalive PH Abstract This pilot study was designed to compare the levels of interleukin-8 (IL-8), a pro-inflammatory chemokine, in the cerebrospinal fluid (CSF) of patients with Guillain-Barre syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), non-inflammatory polyneuropathy (PNP), and other non-inflammatory neurological diseases (functional syndrome or migraine). The results show elevated CSF IL-8 levels in GBS compared to the other groups (p < 0.05). IL-8 could be considered a potential biomarker to differentiate GBS from CIDP. This distinction could be relevant in terms of therapeutic decisions and functional prognosis. PMID: 32096474 [PubMed - in process]
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research