Beyond the burn: Studies on the physiological effects of flamethrowers during World War II

This article examines how the initial absence of scientific data on the physiologic effects of flamethrowers led to an inaccurate understanding of their let hality, and bizarre claims that one of history’s most horrific instruments of war was considered one of the more “humane” weapons on the battlefield.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research

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e C Abstract Hyperbaric oxygen therapy (HBOT) has been shown to improve tissue hypoxia, neovascularization and ischemia reperfusion injury and reduce pathologic inflammation in various clinical settings and was proposed to be a game changer in treatment of burns. Improved and faster wound healing as well as a reduction of morbidity and mortality after thermal and concomitant carbon monoxide poisoning are expected. In defiance of the observed benefits for burn wounds and carbon monoxide poisoning in animal models and few randomized controlled trials there is an ongoing controversy regarding its use, indic...
Source: Wiener Klinische Wochenschrift - Category: General Medicine Authors: Tags: Wien Klin Wochenschr Source Type: research
Inhaled carbon monoxide (CO) displaces oxygen from hemoglobin, reducing the capacity of blood to carry oxygen. Current treatments for CO-poisoned patients involve administration of 100% oxygen; however, when CO poisoning is associated with acute lung injury secondary to smoke inhalation, burns, or trauma, breathing 100% oxygen may be ineffective. Visible light dissociates CO from hemoglobin. We hypothesized that the exposure of blood to visible light while passing through a membrane oxygenator would increase the rate of CO elimination in vivo. We developed a membrane oxygenator with optimal characteristics to facilitate ex...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
BACKGROUND: Carbon monoxide (CO) is a major and ubiquitous component of fire atmospheres produced when organic matter is burned in an inadequate supply of oxygen. Accidental poisoning by CO is common in cold climates where fireplaces, a gas, electric or ke...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
Authors: Mureşan CO, Zăvoi RE, Dumache RO, Precup CV, Ciocan V, Bulzan OŞ, Florou C, Enache A Abstract Carbon monoxide (CO) remains an insidious and silent killer due to its physical and chemical properties; its lethal effects are encountered in cases of household accidents, occupational hazards or suicide. Deaths due to CO poisoning were studied retrospectively in the period 2000-2018 at the Institute of Forensic Medicine, Timişoara, Romania. These cases represent 1.75% of all the autopsies and 0.63% of all violent deaths. There have been cases of single deaths and cases with multiple victims - concomitant dea...
Source: Romanian Journal of Morphology and Embryology - Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research
Authors: Goggins CA, Khachemoune A Abstract Hyperbaric oxygen therapy (HBOT) is used in the management of a wide array of disease states, including acute thermal burn injuries, carbon monoxide poisoning, and decompression sickness, to name a few. Although HBOT is approved by the Undersea and Hyperbaric Medical Society for the treatment of only 14 conditions, it has been used "off-label" in the management of a variety of dermatological diseases. This review investigates the utilization of HBOT in dermatology and appraises the evidence behind its use. We focus on the role of HBOT in treating necrotizing sof...
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
On Tuesday, the Food and Drug Administration (FDA) announced that several prescription sleep aids must now include aboxed warning—the FDA’s strongest safety warning—following reports of sleepwalking and other rare sleep behaviors that have led to serious injuries and deaths.Sleep aids containing eszopiclone (Lunesta), zaleplon (Sonata), and zolpidem (Ambien, Ambien CR, Edluar, Intermezzo, and Zolpimist) must carry the boxed warning as well as another warning against the use of the medications by patients with a history of sleepwalking or other rare sleep behaviors like sleep driving.This is not the first ...
Source: Psychiatr News - Category: Psychiatry Tags: Ambien Ambien CR and Zolpimist boxed warning Edluar eszopiclone FDA insomnia Intermezzo lunesta sleepwalking Sonata zaleplon zolpidem Source Type: research
AbstractInhalation injury is often associated with burns and significantly increases morbidity and mortality. The main toxic components of fire smoke are carbon monoxide, hydrogen cyanide, and irritants. In the case of an incident at a nuclear power plant or recycling facility associated with fire, smoke may also contain radioactive material. Medical treatments may vary in different countries, and in this paper, we discuss the similarities and differences in the treatments between China and Germany. Carbon monoxide poisoning is treated by 100% oxygen administration and, if available, hyperbaric oxygenation in China as well...
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research
CHICAGO (AP) — The dangerous cold and heavy snow that hobbled the northern U.S. this week has retreated, but not before exacting a human toll: more than two dozen weather-related deaths in eight states and hundreds of injuries, including frostbite, broken bones, heart attacks and carbon monoxide poisoning. In Illinois alone, hospitals reported more than 220 cases of frostbite and hypothermia since Tuesday, when the polar vortex moved in and overnight temperatures plunged to minus 30 (minus 34 Celsius) or lower — with wind chills of minus 50 (minus 45 Celsius) or worse in some areas. Hennepin Healthcare in Minne...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Tags: Patient Care News Source Type: news
Although carbon monoxide (CO) poisoning presents infrequently, it is a consequential and serious component of burn-related injuries, especially those injured via structure fire. A multitude of retrospective reviews and prospective trials have attempted to establish evidence demonstrating the ideal modality for oxygen administration in CO-poisoned patients; however, a consensus recommendation has not been reached. Given that half of fire-related patients succumb to CO poisoning, this is an imperative area of research.
Source: Journal of Trauma Nursing - Category: Nursing Tags: PHARMACOLOGY EDITORIAL Source Type: research
The primary danger with underground mine fires is carbon monoxide poisoning. A good knowledge of smoke and carbon monoxide movement in an underground mine during a fire is of importance for the design of ventilation systems, emergency response, and miners'...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
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