Prevalence of Chronic Kidney Disease and Associated Factors among Patients with Diabetes in Northwest Ethiopia: A Hospital-Based Cross-Sectional Study

Publication date: Available online 26 February 2020Source: Current Therapeutic ResearchAuthor(s): Hailemaryam Alemu, Workagegnehu Hailu, Aynshet Adane
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research

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AstraZeneca has announced that the phase 3 DAPA-CKD trial for dapagliflozin (Farxiga) in patients with chronic kidney disease has been halted early because of overwhelming efficacy.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Authors: Kawada T PMID: 32216510 [PubMed - as supplied by publisher]
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Authors: Viswanathan V, Jamthikar AD, Gupta D, Puvvula A, Khanna NN, Saba L, Viskovic K, Mavrogeni S, Turk M, Laird JR, Pareek G, Miner M, Ajuluchukwu JNA, Sfikakis PP, Protogerou A, Kitas GD, Nicolaides A, Sharma A, Suri JS Abstract BACKGROUND: Recently, a 10-year image-based integrated calculator (called AtheroEdge Composite Risk Score-AECRS1.0) was developed which combines conventional cardiovascular risk factors (CCVRF) with image phenotypes derived from carotid ultrasound (CUS). Such calculators did not include Chronic Kidney Disease (CKD)-based biomarker called estimated glomerular filtration rate (eGFR). The...
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
We read with great interest the article by Byrne et  al. who summarized recent advances in the association between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD), and reported that the prevalence rate of CKD in patients with NAFLD ranged from 20% to 55%.1 Given a high cardiovascular disease-specific mortality among NAFLD populations (4.79 per 1,000 person-years, 95% CI 3.43–6.70), NAFLD-related cardiovascular events have filtered into people's minds.2 By contrast, although CKD is another closely related extrahepatic disease, the burden of CKD, especially the incidence of CKD, has not ...
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
The multiple endocrine functions of bone other than those related to mineral metabolism, such as regulation of insulin sensitivity, glucose homeostasis, and energy metabolism, have recently been discovered. In vitro and murine studies investigated the impact of several molecules derived from osteoblasts and osteocytes on glucose metabolism. In addition, the effect of glucose on bone cells suggested a mutual cross-talk between bone and glucose homeostasis. In humans, these mechanisms are the pivotal determinant of the skeletal fragility associated with both type 1 and type 2 diabetes. Metabolic abnormalities associated with...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This study included 1962 patients who underwent transesophageal echocardiographic examination (TEE) prior to cardioversion or ablation in the years 2014-2018 in three cardiac centers. RESULTS: More than a quarter of AF patients had decreased eGFR (
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
her J Abstract OBJECTIVES: We aimed to assess the hypertension (HTN) awareness and associated factors in France. METHODS: We conducted a cross-sectional analysis using data from the CONSTANCES population-based cohort involving 87,808 volunteer participants included between 2012 and 2018. HTN was defined as average blood pressure (BP) over 140/90 or use of BP medication, awareness as self-reported HTN. Multivariable logistic regression models were used to identify the associated factors. RESULTS: Overall, 27,160 hypertensive participants (men = 16,569) above 18 years old were analyzed. Hypertension awaren...
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research
AbstractChronic kidney disease is a prevalent complication of type 2 diabetes mellitus (T2DM). Sodium-glucose cotransporter type 2 inhibitors (SGLT2is) have a unique mode of action targeting the kidney. As their glucose-lowering potency declines with the reduction in estimated glomerular filtration rate, their clinical use in patients with T2DM with chronic kidney disease has been submitted to restriction. However, recent observations demonstrated that SGLT2is reduce the progression of renal impairment in patients with mild-to-moderate chronic kidney disease, with or without albuminuria. Furthermore, SGLT2is reduce the inc...
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research
In conclusion, coronary spasms during provocation tests with ER independently correlated with the MB. MB may predict coronary spasms.
Source: Heart and Vessels - Category: Cardiology Source Type: research
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