Label-free peptide quantification coupled with in silico mapping of proteases for identification of potential serum biomarkers in gastric adenocarcinoma patients.

CONCLUSION: Our experimental results demonstrate that the serum levels of peptides were significantly differentiated in GAC physiopathology. The hypotheses built on protease regulation could be used for further investigations to measure proteases and their activity levels that have been poorly studied for GAC diagnosis.
PMID: 32097616 [PubMed - as supplied by publisher]

Source: Clinical Biochemistry - February 21, 2020 Category: Biochemistry Authors: Mendes de Oliveira T, Thalles Jocelino Gomes de Lacerda J, Gianini Figueiredo Leite G, Dias M, Anita Mendes M, Kassab P, Glaucielly Sales E Silva C, Aparecida Juliano M, Manoukian Forones N Tags: Clin Biochem Source Type: research