Basal cell carcinoma invasion depth determined with 30 and 75 MHz high-frequency ultrasound and histopathology - a comparative study.
CONCLUSIONS: In cases of BCCs with thickness of ≤1 mm, there was a high correlation (r=0.870) of the tumor spread depth between micromorphological measurements and the results obtained using a 75 MHz transducer and in cases of BCCs with thickness of>1 mm, a very high correlation (r=0.951) of the tumor spread depth was observed between histomorphometry and30 MHz transducer measurements. PMID: 32096785 [PubMed - as supplied by publisher]
Authors: Vatamanesku I, Parasca SV, Parasca OM, Vaida FA, Mehedinţi MC, Grosu F, Ciurea ME Abstract Basal cell carcinoma (BCC) is the most frequent skin cancer and its location in the nasal pyramid poses treatment problems. The main issue is how large the resection margins should be. The article presents a retrospective study on patients with BCCs of the nose. Thirty-seven patients were included and the correlations between incomplete resections and tumor dimensions, resection margins or histological sub-type were investigated. Of the 37 patients, only five had tumor-positive excision margins, but no correlation w...
Authors: Suozzi K, Turban J, Girardi M Abstract Ultraviolet radiation (UVR) exposure is well established as the major environmental risk factor for the development of melanoma, cutaneous squamous cell carcinoma (cSCC), and basal cell carcinoma (BCC). Additional risk factors including genetic mutations, other environmental agents, and immune status are important in modulating the effects of UVR. Dermatologists advocate a multi-pronged approach to minimizing UVR exposure including lifestyle modifications, UVR protective clothing, and topically applied sun-protective products, i.e. sunscreen. New Federal Drug Administ...
ConclusionsOur retrospective analysis focused on the use of a novel therapeutic scheme based on prolonged use of vismodegib after CR of the laBCC. The results demonstrate that the maintenance dose of vismodegib described herein effectively eliminated skin tumor recurrence and reduced the severity of common adverse events, thus increasing patient compliance.
Mrs. S is an 85-year-old woman who moved into the nursing home five years ago when her husband could no longer provide care for her due to her progressive weakness and failure to thrive. She has a history of Barrett ’s esophagus and significant reflux and subsequent dysphagia, a long history of depression, allergic rhinitis, dementia with a Brief Interview for Mental Status (BIMS) score of 12, basal cell carcinoma, insomnia, iron deficiency anemia, and a pneumonitis due to aspiration. She is oxygen dependent.
This study was undertaken to identify risk factors using the UNOS database.
We thank van Delft et al. for their letter to the Editor related to our published European consensus-based interdisciplinary guidelines on the diagnosis and treatment of basal cell carcinoma (BCC) . They comment on the extensive safety margins for conventional (2D) surgical excision of high-risk BCCs and the prop osed frequent follow-up of patients with a history of BCC.
CONCLUSIONS: This new guideline answers the working group's clinical questions about the routine management of BCC in Spain. It provides dermatologists with a tool they can use for decision-making while taking into consideration the resources available and patient preferences. PMID: 32241529 [PubMed - as supplied by publisher]
Condition: Basal Cell Carcinoma of the Head and Neck Interventions: Drug: Pembrolizumab; Other: Tissue collection Sponsor: Brian Gastman Not yet recruiting
No abstract available