Effect of Traditional Chinese Medicine Bufei Granule on Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis Based on Existing Evidence.

Effect of Traditional Chinese Medicine Bufei Granule on Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis Based on Existing Evidence. Evid Based Complement Alternat Med. 2020;2020:3439457 Authors: Fan Y, Wen X, Zhang Q, Wang F, Li Q, Li X, Guo Y Abstract This systematic review and meta-analysis aimed at evaluating the effect of traditional Chinese medicine (TCM) Bufei granule on stable chronic obstructive pulmonary disease (COPD). We retrieved data from PubMed, Web of Science, EMBASE, the Cochrane Central Register of Controlled Trials, CNKI, Wanfang, and WeiPu (VIP) for studies focusing on whether the TCM Bufei granule would be effective in treating stable COPD. No language restriction and blinding were used. All trials involved were examined based on the standards of the Cochrane Handbook, and Review Manager 5.3 software was applied for analyzing data. We included four studies involving 599 patients with stable COPD. When compared to placebo treatment, TCM Bufei granule intervention exhibited improvement in the forced expiratory volume in one second (FEV1) (standardized mean difference (SMD) = 0.70; range, 0.50-0.91; I 2 = 0%), forced vital capacity (FVC) (SMD = 0.43; range, 0.23-0.62; I 2 = 0%), FEV1 percentage of predicted value (FEV1%) (SMD = 0.57; range, 0.38-0.76; I 2 = 4%), and FEV1/FVC (SMD = 0.69; range, 0.50-0.87; I 2 = 0%). There was a statistically signific...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research