Synaptic Correlates of Anterograde Amnesia and Intact Retrograde Memory in a Mouse Model of Alzheimer's Disease.

CONCLUSION: Our data suggest that in the early AD stages synaptic plasticity of CA1 synapses, crucial to form new memories, is lost, while plasticity of aCC synapses is intact and contributes to the persistence of long-term memories. PMID: 32091333 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32091333?dopt=Abstract

Source: Current Alzheimer Research - February 23, 2020 Category: Neurology Authors: Rizzello E, Middei S, Marchetti C Tags: Curr Alzheimer Res Source Type: research