Mixed-beam approach in locally advanced nasopharyngeal carcinoma: IMRT followed by proton therapy boost versus IMRT-only. Evaluation of toxicity and efficacy.

Conclusions: Sequential MB approach for LANPC patients provides a significantly lower acute toxicity profile compared to full course of IMRT. There were no differences in early-late morbidities and disease-related outcomes (censored at two-years) but a longer follow-up is required to achieve conclusive results.
PMID: 32090645 [PubMed - as supplied by publisher]

Source: Acta Oncologica - February 22, 2020 Category: Cancer & Oncology Authors: Alterio D, D'Ippolito E, Vischioni B, Fossati P, Gandini S, Bonora M, Ronchi S, Vitolo V, Mastella E, Magro G, Franco P, Ricardi U, Krengli M, Ivaldi G, Ferrari A, Fanetti G, Comi S, Tagliabue M, Verri E, Ricotti R, Ciardo D, Jereczek-Fossa BA, Valvo F, O Tags: Acta Oncol Source Type: research