Flortaucipir-PET, blood samples link brain injuries to CTE

Flortaucipir-PET and blood tests have correlated two key biomarkers of chronic...Read more on AuntMinnie.comRelated Reading: Flortaucipir-PET shows moderate promise for CTE PET shows tau better predicts brain atrophy than amyloid Flortaucipir-PET shows tau accumulation after one TBI PET's view of tau could explain women's early dementia Studies question link between contact sports and CTE
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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CONCLUSIONS: Our study results corroborate earlier findings that the CSF tool is of added value to the diagnostic workup in daily clinical practice outside tertiary referral centers. CSF levels can best be used in patients under 66 years of age. Given the limited use of this tool in settings outside research facilities, we recommend that the usefulness of CSF biomarkers is studied in a multicenter study. When in the future CSF levels can be reliably measured in plasma, this may become even more relevant. PMID: 32224618 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
CONCLUSION: Our findings provide further support that MCI reversion to normal cognitive functioning as well as re-transitioning to MCI is fairly common, suggesting that the MCI trajectory does not necessarily lead straight to dementia. Additionally, assessment of factors associated with reversion can aid clinicians to make accurate MCI progression prognosis. PMID: 32224608 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Authors: Almeida-Meza P, Steptoe A, Cadar D Abstract BACKGROUND: In the current climate of an ageing population, it is imperative to identify preventive measures for dementia. AIMS: We implemented a multifaceted index of cognitive reserve markers and investigated dementia incidence over 15 years of follow-up in a representative sample of the English population. METHOD: Data were 12 280 participants aged ≥50 years from the English Longitudinal Study of Ageing, free from dementia at their baseline assessments during wave 1 (2002-2003), 3 (2006-2007) or 4 (2008-2009), and followed up until wave 8 (2016-2017...
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
CONCLUSION: OAB is the most common lower urinary tract symptom in LBD often associated with detrusor overactivity, and less frequently voiding difficulties sometimes associated to prostatism. LEVEL OF EVIDENCE: 3. PMID: 32224094 [PubMed - as supplied by publisher]
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Authors: Khosravi S, Harner ME Abstract Mitochondria perform a plethora of functions in various cells of different tissues. Their architecture differs remarkably, for instance in neurons versus steroidogenic cells. Furthermore, aberrant mitochondrial architecture results in mitochondrial dysfunction. This indicates strongly that mitochondrial architecture and function are intimately linked. Therefore, a deep knowledge about the determinants of mitochondrial architecture and their function on a molecular level is of utmost importance. In the past decades, various proteins and protein complexes essential for formatio...
Source: Biological Chemistry - Category: Chemistry Tags: Biol Chem Source Type: research
Publication date: Available online 31 March 2020Source: Journal of Clinical NeuroscienceAuthor(s): Raimundo Nonato Campos-Sousa, Icaro Araújo de Sousa, Kelson James Almeida, Inácio Augusto Dias de Castro, Marconi Cosme Soares de Oliveira-Filho, Elizabeth M.A.B. Quagliato
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
No abstract available
Source: Neurology Today - Category: Neurology Tags: In the Pipeline Source Type: research
Authors: Matsumura E, Nohara K, Tanaka N, Fujii N, Sakai T Abstract Polypharmacy in elderly persons living at home or in a nursing home is an issue. In the field of dentistry, strategies to reduce polypharmacy must be promoted; however, there is insufficient basic data on medications received by elderly persons with dysphagia living at home or in a nursing home. The subjects were 106 elderly persons with dysphagia living at home or in a nursing home. Based on their medical records, the presence of disease and number/type of drugs being administered were investigated. Stroke, dementia, and hypertension were common. ...
Source: Journal of oral science - Category: Dentistry Tags: J Oral Sci Source Type: research
Photo credit Caleb George Dear Candid Caregiver: My parents were always open about their long-term plans for retirement, saying that they’ve worked hard and retirement was going to be the payoff. Travel was huge on the horizon. Now, my dad has been diagnosed with mixed dementia, which, in his case, means Alzheimer’s and possibly Lewy body dementia, so their dreams are pretty much canceled. Mom is, for the most part, a good caregiver, but she’s resentful about what happened, and why wouldn’t she be? She has a right to these feelings except that her resentment shows through to Dad through her bod...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
In conclusion, the different severities of glaucoma do not alter the incidence of subsequent dementia.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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