Diagnostic Accuracy of Holotranscobalamin, Vitamin B12, Methylmalonic Acid, and Homocysteine in Detecting B12 Deficiency in a Large, Mixed Patient Population.

In conclusion, in women < 50 years and in men, HoloTC, MMA, or Hcy do not appear superior to B12 for the detection of B12 deficiency. For women 50 years and older, HoloTC seems to be the preferred first-line marker for the detection of subclinical B12 deficiency. PMID: 32089757 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32089757?dopt=Abstract

Source: Disease Markers - February 25, 2020 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

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