Prospective Analysis and Comparison of Periareolar Excision (Delivery) Technique and Pull-Through Technique for the Treatment of Gynecomastia
To investigate the feasibility of single-port endoscopic mastectomy via the lateral chest approach in the treatment of Simon grade II gynecomastia. Data from 12 patients with grade II gynecomastia admitted from January 2017 to November 2018 were retrospectively analyzed, and related satisfaction surveys were conducted 6 months after the operation. All surgeries were successfully performed under single-port endoscopy, and no patients were converted to open surgery. There were no serious complications related to the surgery, and all the patients were satisfied with the postoperative appearance. The application of single-p...
Publication date: Available online 11 May 2020Source: Academic RadiologyAuthor(s): Mohamad Ali Kazemi, Samira Hemmati, Behnaz Moradi, Hashem Sharifian, Kavous Firooznia, Nasrin Nikravangolsefid
In this study, we describe two male siblings with mild intellectual disability, global developmental delay, short stature, microcephaly, and nyctalopia. Whole exome sequencing of the affected siblings and the parents identified a missense var iant (c.413C > G) in thePHF6 gene, which leads to alteration of a serine residue at position 138 to cysteine. This mutation is located in a highly conserved region. Sanger sequencing confirmed the segregation of this mutation in the family in an X-linked recessive fashion. Multiple mass spectrometry-based proteomic studies have reported phosphorylation at serine 138 ...
We report a case that occurred in the breasts of a 62-year-old man. A clinical diagnosis of gynecomastia was initially made. Partial mastectomy was done and MSL was reported on histopathologic examination. Our literature search revealed no previous case of MSL in the breast reported from our environment.
Background: 47,XXY commonly known as Klinefelter syndrome (KS) is the most common male sex chromosome aneuploidy. The syndrome is characterized by hypotonicity, developmental delays, learning disabilities, and psychosocial problems during infancy/childhood and low testosterone production (hypogonadism) in adolesence/adulthood. Untreated, adolescents and adults may develop gynecomastia, osteoporosis and most commonly, infertility. The current standard of care offers treatment for KS at the onset of puberty for boys following molecular diagnosis.
In conclusion, immunoglobulins exhibit limited benefit on immune ‐neuropathy in patients with coexisting KD.
Conditions: Gynecomastia; Delayed Wound Healing Interventions: Drug: Nitroglycerin Paste; Drug: Dermabond Sponsor: Icahn School of Medicine at Mount Sinai Recruiting
Conclusions: Combining PBRT, PLNRT, and LT-ADT had an acceptable PFS in patients with significant post-operative risk factors for recurrence. While therapy was well-tolerated, long-term hypogonadism was a substantial risk. Further investigations are needed to determine if this combination is beneficial.Trial registration: NCT01255891.