Advanced maternal age and in  vitro fertilization: to inject or to inseminate? That is the question

We have known for over 40 years that in the setting of in  vitro fertilization (IVF), having poor semen parameters will often lead to poor fertilization rates, resulting in suboptimal reproductive outcomes) (1). Overcoming this “male factor” infertility with the use of intracytoplasmic sperm injection (ICSI) has arguably been among the biggest revolut ions in IVF practice since its first use in 1992. As pointed out by Sunderam et al. (2), the use of ICSI has increased dramatically in the United States over the past two decades, with some clinics reporting using ICSI in all or nearly all IVF cycles.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research