Cytomegalovirus infection during pregnancy: State of the science

Cytomegalovirus is the most common congenital infection, affecting 0.5-2% of all live births and the main non-genetic cause of congenital sensorineural hearing loss and neurological damage. Congenital CMV can follow maternal primary infection or non-primary infection. Sensori-neurological morbidity is confined to the first trimester with up to 40-50% of infected neonates developing sequelae after first trimester primary infection. Serological testing before 14 weeks is critical to identify primary infection within three months around conception but is not informative in women already immune before pregnancy.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Expert Review Source Type: research