Interplay between PCI access site, anticoagulant agent, and bleeding: Insights from the REGULATE-PCI randomized trial

Publication date: Available online 24 February 2020Source: American Heart JournalAuthor(s): Guillaume Marquis-Gravel, Zhen Huang, Steven L. Zelenkofske, A. Michael Lincoff, Roxana Mehran, P. Gabriel Steg, Christoph Bode, John H. Alexander, Thomas J. Povsic
Source: American Heart Journal - Category: Cardiology Source Type: research

Related Links:

Conclusion: We report a 33.9% positive yield, with 65.8% of patients undergoing further workup as a result of CE and 12.7% requiring therapeutic intervention. We conclude that CE plays an important role in the investigation of IDA and occult gastrointestinal bleeding and has important implications on further management.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research
Authors: Ying S, Liping Z, Zhulin G, Yanhong D, Liang G Abstract Background: Arm choice for peripherally inserted central catheter (PICC) insertion is often determined by PICC nurses.Objectives: To explore the impact of arm choice (dominant or non-dominant) on the rate of catheter-related complications and degree of comfort in patients with PICCs.Design: A cross-sectional study.Methods: We used questionnaires and scales to collect 255 patients' general information, catheter-related complications and comfort degree. They were divided into two groups (PICC inserted in the dominant or non-dominant arm).Results: There ...
Source: Contemporary Nurse - Category: Nursing Tags: Contemp Nurse Source Type: research
Conclusion Dual antithrombotic and NOAC regimens have reduced bleeding without compromising the risk of cardiovascular events or mortality, and should be preferred for patients with ACS or PCI also needing long-term anticoagulation.
Source: Coronary Artery Disease - Category: Cardiology Tags: Anti-platelet therapy Source Type: research
Conclusion Prolonged DAPT reduces cardiac mortality and major adverse cardiovascular events in complex PCI. The results would need confirmation in a larger randomized study.
Source: Coronary Artery Disease - Category: Cardiology Tags: Anti-platelet therapy Source Type: research
Conclusion: In this small exploratory study, HTPR was frequent in PAD patients. Furthermore, the results are suggestive that MALE might be associated with dual HTPR. This leads to the hypothesis that optimized antithrombotic regimens post percutaneous transluminal angioplasty should be tested in clinical trials. PMID: 32252582 [PubMed - as supplied by publisher]
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
This study aimed to study the endoscopic yield, appropriateness, and complications of pediatric endoscopy performed by adult gastroenterologists in an adult endoscopic suite. Methods: This a retrospective study in which records of all the patients less than 18 years of age who underwent endoscopy in the last 5 years were studied. The indications of endoscopy in children were categorized as appropriate or inappropriate per the latest guidelines by American Society for Gastrointestinal Endoscopy and North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Positive endoscopic yield was defined as t...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Authors: Jeong DK, Lee JW, Choi SJ, Bae YC Abstract Infantile hemangiomas have a growth phase and an involution phase. For this reason, serial observation has generally been recommended as the treatment for uncomplicated infantile hemangiomas. Recently, however, individualized approaches have been emphasized. Although cleft lip and infantile hemangioma are common congenital diseases, infantile hemangiomas on the cleft side (i.e., in the operative field of the cleft lip) are extremely rare, and no clear guidelines have been established for their treatment. We experienced a case in which a patient with a cleft lip ha...
Source: Archives of Plastic Surgery - Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research
A 28-year-old Chinese man presented to the emergency department (ED) with acute onset of abdominal distension, generalized abdominal pain, and repeated vomiting. There was no fever, diarrhea, or gastrointestinal bleeding. He reported chronic constipation requiring ED attendance five years ago due to abdominal distension and nausea, but his bowel habit had not changed recently.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Diagnostic Dilemma Source Type: research
Conclusion: HBO treatment might have the potential to alleviate radiotherapy-related gastrointestinal complications, including rectal bleeding, diarrhea, and pain, but more data are needed for further conclusions. Other symptoms were not further analyzed, as the number of studies was insufficient. More large-scale and prospective studies are needed for better evaluation of HBO's therapeutic values.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
las Janus Direct oral anticoagulants (DOAC) are now recommended for the treatment of cancer-associated thrombosis (CAT) based on the results of dedicated trials demonstrating that DOAC are non-inferior to low molecular weight heparins in preventing recurrent venous thromboembolism (VTE) in this population. The definition of “cancer patient” differs substantially among studies. Whether patients with active cancer and those with a history of cancer (HOC) carry the same risks of recurrent VTE and bleeding remains unclear. Few studies reported data on the efficacy and safety of anticoagulants according ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Perspective Source Type: research
More News: Bleeding | Cardiology | Heart