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Source: OnMedica Latest News - Category: UK Health Source Type: news

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The Model for End-stage Liver Disease (MELD) organ allocation system has led to sex disparities, with women less likely to receive a deceased donor liver transplant (DDLT) and more likely to die on the waiting list, researchers say.Reuters Health Information
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Transplantation News Source Type: news
Diabetes mellitus is the 7th leading cause of death worldwide according to the World Health Organization. The rate of obesity has reached epidemic proportions in westernized countries. Non-alcoholic fatty liver disease (NAFLD) is associated with diabetes and obesity and is currently a leading etiology for liver transplantation in the United States. The duodenum plays an important role in nutrient absorption and glucose metabolism. Duodenal mucosal resurfacing (DMR) is a novel endoscopic technique of hydrothermal ablation of the duodenal mucosa potentially improving glycemic control.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Poster abstracts Source Type: research
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - Category: General Medicine Source Type: research
is a highly lethal biliary epithelial tumor that is rare in the general population but has increased rates in patients with primary sclerosing cholangitis (PSC). It is heterogenous, and management varies by location. No effective prevention exists, and screening is likely only feasible in PSC. Patients often present in an advanced state with jaundice, weight loss, and cholestatic liver enzymes. Diagnosis requires imaging with magnetic resonance cholangiopancreatography, laboratory testing, and endoscopic retrograde cholangiopancreatography. Potentially curative options include resection and liver transplant with neoadjuva...
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research
Kramer struggled with illness for much of his adult life, including infection with the AIDS-causing HIV virus. He also had a liver disease and required a liver transplant.
Source: WebMD Health - Category: Consumer Health News Source Type: news
There is limited evidence linking achievement of biochemical response with outcomes in Autoimmune Hepatitis (AIH), and it is unclear whether normalization of serum immunoglobulin G (IgG) levels influences prognosis.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Liver, Pancreas and Biliary Tract Source Type: research
Conclusions: Our results confirm the efficacy of the liver transplantation to achieve of a good QOL. Furthermore, these patients seem to maintain high therapeutic adherence, thus ensuring a good outcome of the care received during the transplantation process.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Abstract Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated chronic liver diseases. PSC is a rare disorder characterized by multi-focal bile duct strictures and progressive liver diseases that ultimately results in the need for liver transplantation in most patients. Imaging studies, such as MRCP, have an essential role in the diagnosis of most cases of PSC. PSC is usually accompanied by inflammatory bowel disease, and there is a high risk of cholangiocarcinoma and colorectal cancer in PSC. No medical therapies have been proven to delay the progression of PSC. Endoscopic...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
ConclusionsThis is the first consensus clinical guidance synthesized by APASL for our hepatologist and their allied medical personal.
Source: Hepatology International - Category: Infectious Diseases Source Type: research
Liver transplantation (LT) offers excellent long-term outcome for certain patients with hepatocellular carcinoma (HCC), with a push to not simply rely on tumor size and number. Selection criteria should also consider tumor biology (including alpha-fetoprotein), probability of waitlist and post-LT survival (ie, transplant benefit), organ availability, and waitlist composition. These criteria may be expanded for live donor LT (LDLT) compared to deceased donor LT though this should not adversely affect the double equipoise in LDLT, namely ensuring both acceptable recipient outcomes and donor safety. HCC patients with compensa...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
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