MRI reveals brain changes from Parkinson's disease

An MRI technique known as quantitative susceptibility mapping reveals that...Read more on AuntMinnie.comRelated Reading: MRI measurements of iron content show impact of stroke Iron particles could lead to MRI contrast alternative MRI links iron in the brain to multiple sclerosis DWI-MRI shows vision changes could predict Parkinson's DTI-MRI sheds light on Parkinson's disease
Source: Headlines - Category: Radiology Source Type: news

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CONCLUSION: Partial bladder recovery has been evident after SC therapy in SCI models. Due to limitations in the number of studies in other neurological diseases, additional studies are necessary to confirm the detailed mechanism for bladder recovery. PMID: 33017895 [PubMed]
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
Telemedicine is the provision of health care services to a patient separated from the physician by a distance, with the help of information technologies and telecommunication[1]. In recent years, there is quick advancement of scope and usage of telemedicine in the field of neurology, also referred to as teleneurology. Beginning with acute stroke care, it is fast expanding to the care of persons with multiple sclerosis, Parkinson ’s disease, and epilepsy[2–6]. The two key factors driving the ever-increasing demand for telemedicine in Neurology are limited access to specialists (Neurologists) and difficulties fac...
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
The current COVID-19 pandemic presents unprecedented new challenges to public health and medical care delivery. To control viral transmission, social distancing measures have been implemented all over the world, interrupting the access to routine medical care for many individuals with neurological diseases. Cognitive disorders are common in many neurological conditions, e.g., stroke, traumatic brain injury, Alzheimer's disease, and other types of dementia, Parkinson's disease and parkinsonian syndromes, and multiple sclerosis, and should be addressed by cognitive rehabilitation interventions. To be effective, cognitive reh...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
CONCLUSIONS AND RELEVANCE: HMD-VR is an emerging technology with many uses in adult physical rehabilitation. Higher quality clinical implementation studies are needed to examine effects on patient outcomes. WHAT THIS ARTICLE ADDS: We review existing research on how immersive virtual reality (e.g., using head-mounted displays) has been used for different clinical populations in adult physical rehabilitation and highlight emerging opportunities in this field for occupational therapists. PMID: 32804624 [PubMed - as supplied by publisher]
Source: The American Journal of Occupational Therapy - Category: Occupational Health Authors: Tags: Am J Occup Ther Source Type: research
Conclusions: This easy, minimally time consuming and effective procedure for isolating and quantifying plasma apoptotic bodies could help physicians to implement the use of such vesicles as a non-invasive tool to monitor apoptosis in patients with cerebrovascular and neurodegenerative diseases for prognostic purposes and for monitoring disease activity. PMID: 32765191 [PubMed]
Source: Biological Procedures Online - Category: Molecular Biology Authors: Tags: Biol Proced Online Source Type: research
AbstractPurpose of ReviewThe goal of this article is to review the major neurologic disorders that can lead to erectile dysfunction (ED) as well as the current management options, highlighting the most recent literature on the subject.Recent FindingsStudies suggest that emerging novel therapies may act to supplement the established therapies for neurogenic ED, such as adipose tissue –derived mesenchymal stem cells and focal muscle vibration. Recent studies and meta-analyses also confirm the safety and efficacy of phosphodiesterase type-5 inhibitors (PDE5i) as the first-line therapy for neurogenic ED.SummaryNeurologic...
Source: Current Sexual Health Reports - Category: Sexual Medicine Source Type: research
Abstract Multiple sclerosis is a progressive autoimmune disorder of the myelin sheath and is the most common inflammatory disease of young adults. Up to 65% of multiple sclerosis patients have cognitive impairments such as memory loss and difficulty in understanding and maintaining attention and concentration. Many pharmacological interventions have been used to reverse motor impairments in multiple sclerosis patients; however, none of these drugs improve cognitive function. Melatonin can diffuse through the blood-brain barrier and has well-known antioxidant and anti-inflammatory properties with almost no side eff...
Source: Journal of Integrative Neuroscience - Category: Neuroscience Authors: Tags: J Integr Neurosci Source Type: research
Abstract Stem cells are considered to have significant capacity to differentiate into various cell types in humans or animals. Unlike specialized cells, these cells can proliferate several times to produce millions of cells. Nowadays, pluripotent stem cells are important candidates to provide a renewable source for replacement of cells in tissues of interest. The damage to neurons and glial cells in the brain or spinal cord is present in neurological disorders such as Amyotrophic lateral sclerosis, stroke, Parkinson's disease, multiple sclerosis, Alzheimer's disease, Huntington's disease, spinal cord injury, lysos...
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research
Abstract ApoD is a 25 to 30 kDa glycosylated protein, member of the lipocalin superfamily. As a transporter of several small hydrophobic molecules, its known biological functions are mostly associated to lipid metabolism and neuroprotection. ApoD is a multi-ligand, multi-function protein that is involved lipid trafficking, food intake, inflammation, antioxidative response and development and in different types of cancers. An important aspect of ApoD's role in lipid metabolism appears to involve the transport of arachidonic acid and the modulation of eicosanoid production and delivery in metabolic tissues. ApoD exp...
Source: Gene - Category: Genetics & Stem Cells Authors: Tags: Gene Source Type: research
Conclusions Despite theoretical concerns about its validity, the PHQ-9 performed well at its standard cut-point of 10. Consistent with the literature, being able to use a validated, brief tool that is available publicly should improve case finding of depression in neurologic populations. When considering clinical practicality along with the findings of this analyzed, this study confirmed that the PHQ-9 is valid in a general outpatient neurologic population.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: Cost effectiveness/economic, Diagnostic test assessment, All Clinical Neurology, Depression, All epidemiology Research Source Type: research
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