Laboratory monkeys are infected with a lethal coronavirus in vaccine hunt

Researchers at the US National Institutes of Health tested an experimental antiviral drug, first created for Ebola, on 18 rhesus macaques.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Discussions with the FDA are ongoing to define the required data set for filing Janssen’s Ebola vaccine regimen under the FDA’s Animal Rule licensure pathway. About Janssen’s Ebola Vaccine Regimen The Janssen investigational preventive Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo) utilizes a viral vector strategy in which viruses – in this case adenovirus serotype 26 (Ad26) and Modified Vaccinia Virus Ankara (MVA) – are genetically modified so that they cannot replicate in human cells. In addition, these vectors are modified to safely carry the genetic code of an Ebola virus protein in order...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
The novel coronavirus strain, severe acute respiratory syndrome coronavirus-2, the causative agent of COVID-19 emerged in Wuhan, China, in December 2019 and is skyrocketing throughout the globe and become a global public health emergency. Despite promising preventive measures being taken, there is no vaccine or drug therapy officially approved to prevent or treat the infection. Everybody is waiting the findings of ongoing clinical trials in various chemical and biological products. This review is specifically aimed to summarize the available evidence and ongoing clinical trials of remdesivir as a potential therapeutic opti...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
On May 1, the U.S Food and Drug Administration issued an emergency-use authorization of remdesivir, an experimental anti-viral drug. With this clearance, doctors in the U.S. are now allowed to use the drug to treat patients with severe cases of COVID-19. Remdesivir isn’t new. It was initially developed to treat Ebola and was also tested in the lab against SARS and MERS—two other coronaviruses that infect humans much like the virus that causes COVID-19. It never made it to the approval stage for those uses, but over the last four months, scientists desperate for options to help mitigate the coronavirus pandemic ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is neither a vaccine nor proven treatment for COVID-19, there is currently an urgent need for effective pharmacotherapy. To address the need for an effective treatment of SARS-CoV-2 during the worldwide pandemic, this systematic review of intravenous (IV) remdesivir was performed. Remdesivir, an anti-viral prodrug originally developed to treat Ebola virus disease, has shown b...
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research
From her laboratory in the far western reaches of Montana, Elizabeth Fischer is trying to help people see what they’re up against in COVID-19. Over the past three decades, Fischer, 58, and her team at the Rocky Mountain Laboratories, part of the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases, have captured and created some of the more dramatic images of the world’s most dangerous pathogens. “I like to get images out there to try to convey that this is an entity, to try to demystify it, so this is something more tangible for people,” says Fischer, on...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
An infectious outbreak can conclude in more ways than one, historians say. But for whom does it end, and who gets to decide?
Source: NYT Health - Category: Consumer Health News Authors: Tags: Epidemics Coronavirus (2019-nCoV) Plague Smallpox Ebola Virus Influenza Epidemic (1918-19) Rats Antibiotics Bubonic Plague Fleas Microbiology Deaths (Fatalities) Vaccination and Immunization your-feed-science your-feed-health Source Type: news
This article is part of #TIME100Talks: Finding Hope, a special series featuring leaders across different fields sharing their ideas for navigating the pandemic. Want more? Sign up for access to more virtual events, including live conversations with influential newsmakers.
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 TIME 100 TIME100 Talks video Source Type: news
On Oct. 2, 2001, a 62-year-old photojournalist named Bob Stevens became the first victim of a coordinated series of anthrax attacks to be admitted to hospital. Stevens inhaled the deadly pathogen after opening one of several letters laced with anthrax spores which were mailed to the offices of prominent senators and media outlets across the U.S. Over the next seven weeks, he and four others would die as a result of their exposure. For a shell-shocked nation still reeling from the single deadliest terrorist attack in human history on September 11, it was a disturbing realization that there was a new wave of challenges to Am...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
A young boy in Pakistan receives an oral polio vaccine (OPV). Credit: Ashfaq Yusufzai/IPSBy Laura MackenzieMay 6 2020 (IPS) Interruptions to vaccination programmes caused by the COVID-19 pandemic could result in new waves of measles or polio outbreaks, health experts warn. A growing number of one-off immunisation campaigns and national routine vaccine introductions are being delayed amid social distancing and other measures to curb the spread of SARS-CoV-2, leaving millions unprotected. With both preventive campaigns and routine immunisations impacted, “we’ll have an increasing number of children who will becom...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health TerraViva United Nations Source Type: news
By Osamu KusumotoTOKYO, May 5 2020 (IPS) The new coronavirus (COVID-19) continues to wreak havoc across the world, as the number of infections and deaths rapidly rise. It has the potential to infect anybody regardless of age or gender. There are grave concerns that the economic fallout from COVID-19 may be comparable to that of the Great Depression. According to Johns Hopkins Coronavirus Resource Center, there are 2,064,668 confirmed cases of COVID-19 and 137,124 deaths due to SARS-CoV-2 (the virus causing COVID-19). In Japan as of noon April 15, there were 8,100 cases of COVID-19 , 119 deaths, and 901 patients discharged ...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Economy & Trade Global Headlines Health Humanitarian Emergencies Poverty & SDGs Source Type: news
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