Lupus nephritis: Multitarget induction therapy versus cyclophosphamide

Nature Reviews Rheumatology 11, 2 (2015). doi:10.1038/nrrheum.2014.203 In a 24-week study of adults with biopsy-proven lupus nephritis, multitarget therapy with tacrolimus (4 mg/day) and mycophenolate mofetil (1 g/day) was more efficacious than intravenous cyclophosphamide (starting dose 0.75 and adjusted to 0.5–1.0 g/m2 body surface area every 4 weeks) as an
Source: Nature Reviews Rheumatology - Category: Rheumatology Tags: Research Highlight Source Type: research