Differences between institutionalized patients and those included in a home care program in Seville.

[Differences between institutionalized patients and those included in a home care program in Seville]. Aten Primaria. 2020 Feb 17;: Authors: Huesa Andrade M, Calvo Gallego JL, Pedregal González MÁ, Bohórquez Colombo P Abstract OBJECTIVES: To describe the characteristics and clinical differences between institutionalised patients and those included in a home care program. DESIGN: A descriptive, observational, cross-sectional, and multicentre study. Site Seville, 2016. STUDY SUBJECTS: A total 1857 elderly patients of similar characteristics (1441 institutionalised and 410 at home) in Seville in 2016. MEASUREMENTS: The variables studied included gender, age, civil status, family support, pathologies, multiple pathology criteria, and medication prescriptions. Functional and cognitive status was evaluated using the Barthel index, and the Lawton-Brody and Pfeiffer scales. RESULTS: The majority of patients (71.40%) were women. The fact of being institutionalised or being included in a home care program were statistically related to the following pathologies and categories: schizophrenia (P
Source: Atencion Primaria - Category: Primary Care Authors: Tags: Aten Primaria Source Type: research

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We reported that, while autophagy was necessary for β cell survival, the highly conserved Sel1L-Hrd1 ERAD protein complex was required for the maintenance of β cell maturation and identity. Using single-cell RNA-Seq, we demonstrated that Sel1L deficiency was not associated with β cell loss, but rather loss of β cell identity. Sel1L-Hrd1 ERAD controlled β cell identity via TGF-β signaling, in part by mediating the degradation of TGF-β receptor 1. Inhibition of TGF-β signaling in Sel1L-deficient β cells augmented the expression of β cell maturation markers and increased the t...
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Authors: Tomiyama H, Shiina K Abstract The brachial-ankle pulse wave velocity (brachial-ankle PWV), which is measured simply by wrapping pressure cuffs around the four extremities, is a simple marker to assess the stiffness of the medium- to large- sized arteries. The accuracy and reproducibility of its measurement have been confirmed to be acceptable. Risk factors for cardiovascular disease, especially advanced age and high blood pressure, are reported to be associated with an increase of the arterial stiffness. Furthermore, arterial stiffness might be involved in a vicious cycle with the development/progression o...
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Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
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Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
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Source: Frontiers in Neurology - Category: Neurology Source Type: research
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