Changes in nucleus accumbens gene expression accompany sex-specific suppression of spontaneous physical activity in aromatase knockout mice.

In conclusion, aromatase ablation leads to gene expression changes in NAc, which may in turn result in reduced SPA and related metabolic abnormalities. These findings may have significance to post-menopausal women and those treated with an aromatase inhibitor. PMID: 32081742 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32081742?dopt=Abstract

Source: Hormones and Behavior - February 16, 2020 Category: Endocrinology Authors: Shay DA, Welly RJ, Givan SA, Bivens N, Kanaley J, Marshall BL, Lubahn DB, Rosenfeld CS, Vieira-Potter VJ Tags: Horm Behav Source Type: research