The interaction between filaggrin mutations and hard domestic water on the risk of early-onset atopic dermatitis.

The interaction between filaggrin mutations and hard domestic water on the risk of early-onset atopic dermatitis. Br J Dermatol. 2020 Feb 21;: Authors: Halling AS, Bager P, Skov L, Zachariae C, Wohlfahrt J, Melbye M, Thyssen JP Abstract We read with interest the article by Jabbar-Lopez et al.,1 showing a significant interaction between filaggrin gene (FLG) loss-of-function mutations and exposure to domestic water hardness (≤256 mg/L versus >256 mg/L calcium carbonate (CaCO3 ) on the risk of atopic dermatitis (AD) at 36 months of age. PMID: 32083316 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32083316?dopt=Abstract

Source: The British Journal of Dermatology - February 20, 2020 Category: Dermatology Authors: Halling AS, Bager P, Skov L, Zachariae C, Wohlfahrt J, Melbye M, Thyssen JP Tags: Br J Dermatol Source Type: research