Inhibition of Maillard reaction in production of low-molecular-weight chitosan by enzymatic hydrolysis
Publication date: Available online 21 February 2020Source: Carbohydrate PolymersAuthor(s): Jun Zhang, Zewen Mei, Xingxi Huang, Yueyue Ding, Yunxiang Liang, Yuxia MeiAbstractA low-molecular-weight chitosan (LMWC) sample was prepared by enzymatic hydrolysis, and used for investigation of special Maillard reaction products (MRPs) and factors affecting LMWC bioactivities. After undergoing MR, LMWC turned to brown color (termed BLMWC), showed reduction of several indices of rice growth promotion. This alteration of bioactivities was attributable to MRPs in BLMWC. A special MRP, 5-hydroxy-2-pyridine methanol isomer (5-H-2PMIS), was identified by HPLC and LC-MS. Analysis of key factors affecting MR, using this MRP as monitoring target compound and OD420 value, suggested that MR process can be minimized by storing LMWC under vacuum in a dry, low-temperature, neutral-pH environment. Na2SO3 was effective for inhibition of MR, at optimal concentration 0.5%. Chemical and FTIR analyses showed that Na2SO3-treated sample conformed to the Chinese National Standard of chitosan (GB 29941-2013). Control of MR is essential for application of LMWC in food, pharmaceutical, and other industries.Graphical abstract
Date: Thursday, 04 30, 2020; Speaker: Staff NIH Library; This class is presented as a webinar only; Videocast Event
Date: Monday, 03 30, 2020; Speaker: R. Burke Squires, Mr., NIAID / OCICB / BCBB; Webinar Only; Videocast Event
Date: Thursday, 04 02, 2020; Speaker: Staff NIH Library; This class is presented as a webinar only. ; Videocast Event
Date: Thursday, 04 09, 2020; Speaker: Zeynup Gumus, Assistant Professor, Ichan School of Medicine at Mount Sinai; https://cbiit.webex.com/mw3300/mywebex/default.do?
Date: Wednesday, 04 22, 2020; Speaker: Staff NIH Library; This class is presented as a webinar only. ; Videocast Event
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