Morphology and size controlled synthesis of co-doped MIL-96 by different alkaline modulators for sensitively detecting α-fetoprotein

Publication date: Available online 21 February 2020Source: Chinese Chemical LettersAuthor(s): Chaonan Gu, Jingjing Li, Guang Yang, Liming Zhang, Chun-Sen Liu, Huan PangAbstractThis work introduces a simple and facile approach for the morphology and size controlled synthesis of Co-doped MIL-96. Using different bases as modulators, Co-doped MIL-96 was obtained with sizes that varied from 5 μm to 300 nm, and four different morphologies, including hexagonal prism, icosahedron, hexagonal spindle and ellipsoid. Among these, nano-sized Co-doped MIL-96 with an ellipsoid morphology exhibited the highest electroactive surface area and good conductivity, as well as the best electrochemical sensing performance towards α-fetoprotein.Graphical abstractCo-doped MIL-96 with different morphologies was successfully prepared via a simple coordination modulation strategy using four different alkaline reagents as cosolvents. Among these, nano-sized Co-doped MIL-96 with an ellipsoid morphology exhibited the highest electroactive surface area and the best electrochemical sensing performance towards α-fetoprotein.
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research