Association between serum amyloid A levels and coronary heart disease: a systematic review and meta-analysis of 26 studies

ConclusionHigh levels of SAA are significantly associated with increased risk of CHD, especially for participants aged more than 55  years, subjects from Europe and Asia, or case–control study. Furthermore, we find that SAA concentrations increased with the severity of CHD. Importantly, our study suggests that high levels of SAA might play a role in CHD by increasing CRP, fibrinogen, IL-6 levels, or attenuating HDL-C levels.
Source: Inflammation Research - Category: Research Source Type: research