Neuroprem: the Neuro-developmental outcome of very low birth weight infants in an Italian region
AbstractIntroductionThe survival of preterm babies has increased worldwide, but the risk of neuro-developmental disabilities remains high, which is of concern to both the public and professionals. The early identification of children at risk of neuro-developmental disabilities may increase access to intervention, potentially influencing the outcome.AimsNeuroprem is an area-based prospective cohort study on the neuro-developmental outcome of very low birth weight (VLBW) infants that aims to define severe functional disability at 2 years of age.MethodsSurviving VLBW infants from an Italian network of 7 neonatal intensive care units (NICUs) were assessed for 24 months through the Griffiths Mental Developmental Scales (GMDS-R) or the Bayley Scales of Infant and Toddler Development (BSDI III) and neuro-functional evaluation according to the International Classification of Disability and Health (ICF-CY). The primary outcome measure was severe functional di sability at 2 years of age, defined as cerebral palsy, a BSDI III cognitive composite score
Conclusion: Medical complexity is common following very preterm birth and has a significant impact on health care use as well as family employment and is more often associated with neurodevelopmental disabilities. Efforts should be deployed to facilitate care coordination upon hospital discharge and to support families of preterm children with medical complexity.Neonatology 2019;115:363 –370
sp;Canadian Neonatal Follow-Up Network Abstract OBJECTIVE: To examine the impact of medical complexity among very preterm infants on health care resource use, family, and neurodevelopmental outcomes at 18 months' corrected age. METHODS: This observational cohort study of Canadian infants born
AbstractThe aims were to investigate mental health problems with the Strength and Difficulties Questionnaire (SDQ) in children born extremely preterm/extremely low birth weight (EP/ELBW) without severe disabilities compared to controls, and to identify peri-, or neonatal factors possibly predicting later mental health problems. A national Norwegian cohort of 11-year-old EP/ELBW children, excluding those with intellectual disabilities, non-ambulatory cerebral palsy, blindness and/or deafness, was assessed. Parents and teachers completed the SDQ. Mean scores and scores ≥90th percentile for the control group, combined (par...
BACKGROUND AND OBJECTIVE: Survival of extremely preterm (EP;
Students at the St Pius X Resource Centre in Malawi for children with physical and developmental disabilities. Credit: Charity Chimungu Phiri/IPSBy Charity Chimungu PhiriBLANTYRE, Malawi, Mar 29 2017 (IPS)When building a house, it’s critical to lay a strong foundation. The same applies to education, with studies showing that children who attend early learning centers perform better in school than those who do not.In Malawi, a 2003 national survey found that only 18.8 percent of school-age children with disabilities were attending class. More than twice as many of the same age group without disabilities (41.1 percent)...
(Abstracted from Int J Gynecol Obstet 2016;134:169–172) Preterm birth (PTB) is responsible for most of the neonatal deaths that occur in the absence of congenital anomalies. It is also a major cause of long-term disabilities, including cerebral palsy, blindness, and deafness in childhood.
CONCLUSIONS: Siblings of a child with CP were at increased risk for a variety of other neurodevelopmental morbidities, as well as early death, indicating the presence of shared underlying causes.
CONCLUSIONS: EP/ELBW children without severe disabilities had increased risk of symptoms of autism, inattention, anxiety, and OCD. Gender differences were comparable to the reference group.
DiscussionThis trial will provide the first direct evidence of the effects of giving preterm babies a higher intake of intravenous protein in the first week after birth on neurodevelopmental outcomes at 2 years corrected age.Trial registrationAustralian New Zealand Clinical Trials Registry: ACTRN12612001084875.
AimsIn a population cohort of children with grey matter injury (GMI) and cerebral palsy (CP), we aimed to describe and classify magnetic resonance imaging characteristics specific to GMI, and to identify key structure–function associations that serve as a basis for rating GMI in clinically relevant ways. MethodSymmetry, extent of cerebral injury, and pathological pattern for 54 children (37 males, 17 females) with CP and a predominant GMI pattern on chronic‐phase magnetic resonance imaging were related to gross motor function, motor type and topography, epilepsy, intellectual disability, blindness, and deafness. Re...