Future Research Prioritization in Cardiac Resynchronization Therapy

Publication date: Available online 21 February 2020Source: American Heart JournalAuthor(s): Marat Fudim, Frederik Dalgaard, Sana M. Al-Khatib, Daniel Friedman, Kathryn Lallinger, William T. Abraham, John G.F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, Daniel E. Schaber, Anthony Tang, Fatima Ali-Ahmed, Sarah Goldstein, Brystana Kaufman, Robyn Fortman, J. Kelly Davis, Lurdes Y.T. Inoue, Gillian D. SandersAbstractBackgroundAlthough cardiac resynchronization therapy (CRT) is effective for some patients with heart failure and a reduced left ventricular ejection fraction (HFrEF), evidence gaps remain for key clinical and policy areas.ObjectiveReview the data on the effects of CRT for patients with HFrEF receiving pharmacological therapy alone or pharmacological therapy and an ICD and then, informed by a diverse group of stakeholders, to identify evidence-gaps, prioritize them and develop a research plan.MethodRelevant studies were identified using PubMed and EMBASE and ongoing trials using clinicaltrials.gov. Forced-ranking prioritization method was applied by stakeholders to reach a consensus on the most important questions.
Source: American Heart Journal - Category: Cardiology Source Type: research