Diets with Low n-6:n-3 PUFA Ratio Protects Rats from Fructose-Induced Dyslipidemia and Associated Hepatic Changes: Comparison between 18:3 n-3 and Long-Chain n-3 PUFA

Dietary fructose plays a critical role in the development of metabolic syndrome (MetS), a metabolic disorder defined by the presence of dyslipidemia, insulin resistance, hypertension, and visceral obesity [1]. Hypertriglyceridemia is a critical component of the MetS and contributes to the development and worsening of other MetS components like insulin resistance [2]. Hypertriglyceridemia increases the risk of developing type 2 diabetes and cardiovascular diseases [3]. Fructose consumption elevates the circulatory triglyceride levels in both human subjects and animal models [4, 5].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Tags: Original research article Source Type: research