Analysis of the Corneal Anterior and Posterior Surface in Patients With Peripheral Hypertrophic Subepithelial Corneal Opacification

Purpose: To characterize the corneal changes in peripheral hypertrophic subepithelial corneal opacification (PHSCO) considering elevation of the anterior and posterior corneal surface, corneal astigmatism, tear secretion, and endothelial cell density. Methods: Thirty-eight eyes of 22 patients with PHSCO on at least 1 eye and 38 eyes of 22 age- and sex-matched healthy subjects were included in this retrospective cross-sectional study. Using the Pentacam system (Oculus, Wetzlar, Germany), measurement of the anterior and posterior corneal surface was performed. In addition, the Schirmer test was conducted, and endothelial cells were counted in the central cornea with a specular microscope (SP-3000P; Topcon, Tokyo, Japan). Results: The mean age was 55.2±11.7 years in patients with PHSCO and 54.1±12.4 years in healthy subjects. The corneas of patients with PHSCO showed higher corneal astigmatism of both the corneal anterior and posterior surface (2.9/0.5 vs. 0.8/0.3 D, PHSCO vs. controls, P=
Source: Eye and Contact Lens: Science and Clinical Practice - Category: Opthalmology Tags: Article Source Type: research