Biclonal light chain gammopathy with aberrant CD33 expression in secondary plasma cell leukemia.

We present a case of a secondary plasma cell leukemia arising from plasma cell myeloma with dual expression of lambda and kappa light chains along with aberrant expression of CD33, CD20, and dim CD56. This case emphasizes the importance of recognizing aberrant immunophenotypes in plasma cell leukemias and represents the first reported case of biclonal light chain expression in a secondary plasma cell leukemia.
PMID: 24133602 [PubMed - in process]

Source: International Journal of Clinical and Experimental Pathology - October 19, 2013 Category: Pathology Authors: Gentry M, Pettenati M, Pang CS Tags: Int J Clin Exp Pathol Source Type: research